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Pregnancy: There is limited amount of data from the use of granisetron in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity (see Pharmacology: Toxicology: Preclinical safety data under Actions). As a precautionary measure, it is preferable to avoid the use of granisetron during pregnancy.
Breast-feeding: It is unknown whether granisetron or its metabolites are excreted in human milk. As a precautionary measure, breast-feeding should not be advised during treatment with Granisetron.
Fertility: In rats, granisetron had no harmful effects on reproductive performance or fertility.
